One Pfizer vaccination 52% effective after 12 days (according to an article in El País in English from 13 January 2021)

Shouldn't we all be believing what the people who actually made the vaccine say instead of government?

Isn't it that simple?
 
Shouldn't we all be believing what the people who actually made the vaccine say instead of government?

Isn't it that simple?
Probably Randy, but it's not quite as black and white as that in a global emergency. Pfizer are specifically missing data from their trials on the efficacy of a one shot vaccination beyond the 3 weeks.

I don't like the way this is going if I am honest but hope I am wrong. Imagine having to start from scratch.
 
Probably Randy, but it's not quite as black and white as that in a global emergency. Pfizer are specifically missing data from their trials on the efficacy of a one shot vaccination beyond the 3 weeks.

I don't like the way this is going if I am honest but hope I am wrong. Imagine having to start from scratch.
That's what I'm saying. Pfizer have recommended the way the vaccine should be administered. So that's how it should be done not how government's determine how it should be done.
 
That's what I'm saying. Pfizer have recommended the way the vaccine should be administered. So that's how it should be done not how government's determine how it should be done.

But they aren't, they have chosen a different path.

Debating it endlessly on here won't change it, if anything it might put people off taking it. We wouldn't want that to happen would we?

One dose or two, hopefully what we can agree on, is that it is important that everyone who is offered the jab takes it up.
 
One of the worries I have had since the start of vaccinations is regarding the plan to have all adults vaccinated by September(unless its changed). Now do the figures for doing this take into account that come around the end of April all those who have had only one dose are going to need their second. Is that in the plan already or is it just going to be a mad dash to get everyone one dose. These things should be discussed now so people know what is coming down the road.
 
But they aren't, they have chosen a different path.

Debating it endlessly on here won't change it, if anything it might put people off taking it. We wouldn't want that to happen would we?

One dose or two, hopefully what we can agree on, is that it is important that everyone who is offered the jab takes it up.
Debate on here won't change things your correct but it's still healthy to have one.

My missus has just been booked in for hers next week. The manager of the home has arranged a nurse to visit and get all the staff done in the same day. She's unclear as to whether the residents will be getting the vaccine the same day as it's technically an assisted living care home and not a traditional full time care home.
 
You really need to read the Israel report as that BBC article does not address why after 14 days efficacy was measured at 33% not 90%.

I get the Pfizer figure of 50% versus 90%, because Pfizer averaged it from day 1. That isn't what the Israel study does and they tested 200,000 people after 14 days where the vaccination is supposed to be approaching its peak effectiveness. That effectiveness was not 90% after 1 dose, but 33% in a real world study, not a lab trial or assumptive conclusions from JVCI.

You really need to listen to what was being said.

Matt Keeling says you wouldn't expect much in the way of efficacy in the first two weeks but then the immune system kicks in & it begins to rise.

"The day after you have the vaccine there's going to be very little difference but as you go forward two weeks three weeks you'd expect to see a much bigger difference as the vaccine efficacy cuts in"

This fits in with the Israel report that says after two weeks they suddenly see a jump from 0 to 33%

"Then we looked to see what is the daily positivity rate... And we saw that there was no difference between vaccinated and unvaccinated until day 14 post-vaccination. But on day 14 post-vaccination, a drop of 33% in positivity was witnessed in the vaccinated group and not in the unvaccinated... this is really good news."

As Pfizer give a figure of 52% over the whole three weeks we know that the efficacy must continue to increase after day 14 so the question really is how high does it go & does it begin to wane before 12 weeks.
 
You really need to listen to what was being said.

Matt Keeling says you wouldn't expect much in the way of efficacy in the first two weeks but then the immune system kicks in & it begins to rise.

"The day after you have the vaccine there's going to be very little difference but as you go forward two weeks three weeks you'd expect to see a much bigger difference as the vaccine efficacy cuts in"

This fits in with the Israel report that says after two weeks they suddenly see a jump from 0 to 33%

"Then we looked to see what is the daily positivity rate... And we saw that there was no difference between vaccinated and unvaccinated until day 14 post-vaccination. But on day 14 post-vaccination, a drop of 33% in positivity was witnessed in the vaccinated group and not in the unvaccinated... this is really good news."

As Pfizer give a figure of 52% over the whole three weeks we know that the efficacy must continue to increase after day 14 so the question really is how high does it go & does it begin to wane before 12 weeks.
Except Pfizer say that at around 2 weeks the efficacy starts to peak.
 
One of the worries I have had since the start of vaccinations is regarding the plan to have all adults vaccinated by September(unless its changed). Now do the figures for doing this take into account that come around the end of April all those who have had only one dose are going to need their second. Is that in the plan already or is it just going to be a mad dash to get everyone one dose. These things should be discussed now so people know what is coming down the road.

Course its in the plan, even if supplies weren't at the level they expected come april they'd prioritise giving people their second dose over giving people their first one.
 

Thanks, I’ve not read that thread, will have a look.
To be clear, I’d prefer the Pfizer doses to be given as per the test data available, and will be happy if the plan changes to do just that.
But I also think that what has been said by the relevant bodies in regards to the dosing regimen also makes sense theoretically. If that’s proven to be wrong by real data as and when it comes in, so be it. I don’t know one way or the other.
 
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